SUcceSS, SUrgery for Spinal Stenosis: protocol of a randomised, placebo-controlled trial.

ABSTRACT:

Introduction

Central lumbar spinal stenosis (LSS) is a common cause of pain, reduced function and quality of life in older adults. Current management of LSS includes surgery to decompress the spinal canal and alleviate symptoms. However, evidence supporting surgical decompression derives from unblinded randomised trials with high cross-over rates or cohort studies showing modest benefits. This protocol describes the design of the SUrgery for Spinal Stenosis (SUcceSS) trial -the first randomised placebo-controlled trial of decompressive surgery for symptomatic LSS.

Methods and analysis

SUcceSS will be a prospectively registered, randomised placebo-controlled trial of decompressive spinal surgery. 160 eligible participants (80 participants/group) with symptomatic LSS will be r

SUBMITTER: Anderson DB 

PROVIDER: S-EPMC6398750 | biostudies-literature | 2019 Feb

REPOSITORIES: biostudies-literature