Association Between Tidal Volumes Adjusted for Ideal Body Weight and Outcomes in Pediatric Acute Respiratory Distress Syndrome.

ABSTRACT:

Objectives

The impact of tidal volume on outcomes in mechanically ventilated children with pediatric acute respiratory distress syndrome remains unclear. To date, observational investigations have failed to calculate tidal volume based on standardized corrections of weight. We investigated the impact of tidal volume on mortality and probability of extubation in pediatric acute respiratory distress syndrome using ideal body weight-adjusted tidal volume.

Design

Retrospective analysis of an ongoing prospective cohort of pediatric acute respiratory distress syndrome patients. Tidal volume was calculated based on actual body weight and two different formulations of ideal body weight.

Setting

PICU at a large, tertiary care children's hospital.

Patients

Pediatric acut

SUBMITTER: Imber DA 

PROVIDER: S-EPMC6399049 | biostudies-literature | 2019 Mar

REPOSITORIES: biostudies-literature