Exposure to tetrachloroethylene-contaminated drinking water and time to pregnancy.

ABSTRACT:

Background

The synthetic solvent tetrachloroethylene (PCE), commonly used in dry cleaning operations, is a human neurotoxicant and carcinogen. However, its effect on reproduction is poorly understood, as prior studies have been limited to small occupational cohorts. We examined the association between PCE exposure from contamination of the public drinking water supply and time-to-pregnancy (TTP) in a cohort of mothers from Cape Cod, Massachusetts.

Methods

The Cape Cod Family Health Study is a retrospective cohort study designed to examine the reproductive and developmental health effects of exposure to PCE-contaminated drinking water. Our analysis included 1565 women who reported 3826 planned pregnancies from 1949 to 1990. Women completed self-administered questionnaires tha

SUBMITTER: Wesselink AK 

PROVIDER: S-EPMC6399737 | biostudies-literature | 2018 Nov

REPOSITORIES: biostudies-literature