An insight into the sialotranscriptome and virome of Amazonian anophelines.

ABSTRACT:

Background

Saliva of mosquitoes contains anti-platelet, anti-clotting, vasodilatory, anti-complement and anti-inflammatory substances that help the blood feeding process. The salivary polypeptides are at a fast pace of evolution possibly due to their relative lack of structural constraint and possibly also by positive selection on their genes leading to evasion of host immune pressure.

Results

In this study, we used deep mRNA sequence to uncover for the first time the sialomes of four Amazonian anophelines species (Anopheles braziliensis, A. marajorara, A. nuneztovari and A. triannulatus) and extend the knowledge of the A. darlingi sialome. Two libraries were generated from A. darlingi mosquitoes, sampled from two localities separated ~ 1100 km apart. A total of 60,016 seque

SUBMITTER: Scarpassa VM 

PROVIDER: S-EPMC6399984 | biostudies-literature | 2019 Mar

REPOSITORIES: biostudies-literature