ZOO: an automatic data-collection system for high-throughput structure analysis in protein microcrystallography.

ABSTRACT: Owing to the development of brilliant microfocus beamlines, rapid-readout detectors and sample changers, protein microcrystallography is rapidly becoming a popular technique for accessing structural information from complex biological samples. However, the method is time-consuming and labor-intensive and requires technical expertise to obtain high-resolution protein crystal structures. At SPring-8, an automated data-collection system named ZOO has been developed. This system enables faster data collection, facilitates advanced data-collection and data-processing techniques, and permits the collection of higher quality data. In this paper, the key features of the functionality put in place on the SPring-8 microbeam beamline BL32XU are described and the major advantages of this system are ou

SUBMITTER: Hirata K 

PROVIDER: S-EPMC6400253 | biostudies-literature | 2019 Feb

REPOSITORIES: biostudies-literature