Exposure to polybrominated diphenyl ethers (PBDEs) during childhood and adiposity measures at age 8 years.

ABSTRACT:

Background

Animal studies suggest polybrominated diphenyl ethers (PBDEs) may be obesogens. However, epidemiologic studies investigating childhood exposure to PBDEs and adiposity are limited, with several reporting an inverse association.

Objectives

To investigate associations between repeated childhood PBDE concentrations and adiposity measures at age 8 years.

Methods

We examined 206 children from the Health Outcomes and Measures of the Environment Study, a birth cohort in Cincinnati, OH (2003-2006). Serum PBDEs were measured at ages 1, 2, 3, 5, and 8 years. We used multiple imputation to estimate missing PBDE concentrations. At 8 years, we measured weight, height, waist circumference, and body fat percentage. We used multiple informant models to estimate age-specific

SUBMITTER: Vuong AM 

PROVIDER: S-EPMC6400314 | biostudies-literature | 2019 Feb

REPOSITORIES: biostudies-literature