Long Non-coding RNAs Coordinate Developmental Transitions and Other Key Biological Processes in Grapevine.

ABSTRACT: Long non-coding RNAs (lncRNAs) are transcripts >200 nucleotides that have prominently surfaced as dynamic regulatory molecules. Using computational approaches, we identified and characterized 56,441 lncRNAs in grapevine (Vitis vinifera) by harnessing RNA-seq data from 10 developmental stages of leaf, inflorescence, and berry tissues. We conducted differential expression analysis and determined tissue- and developmental stage-specificity of lncRNAs in grapevine, which indicated their spatiotemporal regulation. Functional annotation using co-expression analysis revealed their involvement in regulation of developmental transitions in sync with transcription factors (TFs). Further, pathway enrichment analysis revealed lncRNAs associated with biosynthetic and secondary metabolic pathways. Addit

SUBMITTER: Bhatia G 

PROVIDER: S-EPMC6401051 | biostudies-literature | 2019 Mar

REPOSITORIES: biostudies-literature