Transcriptomic analysis of different tissue layers in antler growth Center in Sika Deer (Cervus nippon).

ABSTRACT:

Background

With the unprecedented rapid growth rate (up to 2.75 cm/day), velvet antler is an invaluable model for the identification of potent growth factors and signaling networks for extremely fast growing tissues, mainly cartilage. Antler growth center (AGC) locates in its tip and consists of five tissue layers: reserve mesenchyme (RM), precartilage (PC), transition zone (TZ), cartilage (CA) and mineralized cartilage (MC). The aim of this study was to investigate the transcription dynamics in the AGC using RNA-seq technology.

Results

Five tissue layers in the AGC were collected from three 3-year-old male sika deer using our previously reported sampling method (morphologically distinguishable). After sequencing (15 samples; triplicates/tissue layer), we assembled a referen

SUBMITTER: Ba H 

PROVIDER: S-EPMC6402185 | biostudies-literature | 2019 Mar

REPOSITORIES: biostudies-literature