An efficient algorithm to enumerate sets with fallbacks in a kidney paired donation program.

ABSTRACT: Kidney paired donation is a partial solution to overcoming biological incompatibility preventing kidney transplants. A kidney paired donation (KPD) program consists of altruistic or non-directed donors (NDDs) and pairs, each of which comprises a candidate in need of a kidney transplant and her/his willing but incompatible donor. Potential transplants from NDDs or donors in pairs to compatible candidates in other pairs are determined by computer assessment, though various situations involving either the donor, candidate, or proposed transplant may lead to a potential transplant failing to proceed. A KPD program can be viewed as a directed graph with NDDs and pairs as vertices and potential transplants as edges, where failure probabilities are associated with each vertex and edge. Transplant

SUBMITTER: Wang W 

PROVIDER: S-EPMC6402358 | biostudies-literature | 2019 Mar

REPOSITORIES: biostudies-literature