In utero metal exposures measured in deciduous teeth and birth outcomes in a racially-diverse urban cohort.

ABSTRACT: A growing number of studies have examined associations of metal exposures with birth outcomes, however, results from these studies have been inconsistent, and hampered by methodological limitations. We measured direct fetal exposure to three metals (lead, manganese and zinc) during the second and third trimester and examined its association with birth weight and gestational age at delivery. Participants in the Wayne County Health, Environment, Allergy and Asthma Longitudinal Study (WHEALS), a population-based birth cohort established between September 2003 and December 2007, were invited to donate teeth to the study. Lead, manganese and zinc during the second and third trimesters were measured via high-resolution microspatial mapping of dentin growth rings, a validated biomarker for prenat

SUBMITTER: Cassidy-Bushrow AE 

PROVIDER: S-EPMC6402585 | biostudies-literature | 2019 Apr

REPOSITORIES: biostudies-literature