Multimorbidity and Mental Health-Related Quality of Life and Risk of Completed Suicide.

ABSTRACT:

Background

Physical functioning indexed multimorbidity is strongly associated with long-term mortality, but its role in poor mental health has not been quantified.

Methods

A total of 252 002 community-dwelling adults in the Nurses' Health Study (NHS), NHS II, and Health Professionals Follow-up Study (HPFS) prospective cohorts reported physician-diagnosed diseases and the Short Form-36 over 8 years and had 24-year follow-up for suicide mortality. We quantified multimorbidity using a multimorbidity-weighted index (MWI). We used multivariable-adjusted proportional hazards models with competing risks for suicide mortality and mixed-effects models to estimate mental health-related quality of life (HRQOL).

Results

Multimorbidity was associated with an increased risk of suic

SUBMITTER: Wei MY 

PROVIDER: S-EPMC6402970 | biostudies-literature | 2019 Mar

REPOSITORIES: biostudies-literature