Survival after a cancer diagnosis among solid organ transplant recipients in the United States.

ABSTRACT:

Background

Transplant recipients have an elevated risk of cancer because of immunosuppressive medications used to prevent organ rejection, but to the authors' knowledge no study to date has comprehensively examined associations between transplantation status and mortality after a cancer diagnosis.

Methods

The authors assessed cases in the US general population (N=7,147,476) for 16 different cancer types as ascertained from 11 cancer registries. The presence of a solid organ transplant prior to diagnosis (N=11,416 cancer cases) was identified through linkage with the national transplantation registry (1987-2014). Cox models were used to examine the association between transplantation status and cancer-specific mortality, adjusting for demographic characteristics and cancer st

SUBMITTER: D'Arcy ME 

PROVIDER: S-EPMC6403005 | biostudies-literature | 2019 Mar

REPOSITORIES: biostudies-literature