Associations of hemodynamics, morphology, and patient characteristics with aneurysm rupture stratified by aneurysm location.

ABSTRACT:

Purpose

The mechanisms of cerebral aneurysm rupture are not fully understood. We analyzed the associations of hemodynamics, morphology, and patient age and gender with aneurysm rupture stratifying by location.

Methods

Using image-based models, 20 hemodynamic and 17 morphological parameters were compared in 1931 ruptured and unruptured aneurysms with univariate logistic regression. Rupture rates were compared between males and females as well as younger and older patients and bifurcation versus sidewall aneurysms for different aneurysm locations. Subsequently, associations between hemodynamics and morphology and patient as well as aneurysm characteristics were analyzed for aneurysms at five locations.

Results

Compared to unruptured aneurysms, ruptured aneurysms were ch

SUBMITTER: Detmer FJ 

PROVIDER: S-EPMC6403015 | biostudies-literature | 2019 Mar

REPOSITORIES: biostudies-literature