Inpatient and Outpatient Infection as a Trigger of Cardiovascular Disease: The ARIC Study.

ABSTRACT: Background Acute infections are known cardiovascular disease ( CVD ) triggers, but little is known regarding how CVD risk varies following inpatient versus outpatient infections. We hypothesized that in- and outpatient infections are associated with CVD risk and that the association is stronger for inpatient infections. Methods and Results Coronary heart disease (CHD) and ischemic stroke cases were identified and adjudicated in the ARIC (Atherosclerosis Risk in Communities Study). Hospital discharge diagnosis codes and Medicare claims data were used to identify infections diagnosed in in- and outpatient settings. A case-crossover design and conditional logistic regression were used to compare in- and outpatient infections among CHD and ischemic stroke cases (14, 30, 42, and 90 days before

SUBMITTER: Cowan LT 

PROVIDER: S-EPMC6404437 | biostudies-literature | 2018 Nov

REPOSITORIES: biostudies-literature