Identification of Moonlighting Proteins in Genomes Using Text Mining Techniques.

ABSTRACT: Moonlighting proteins is an emerging concept for considering protein functions, which indicate proteins with two or more independent and distinct functions. An increasing number of moonlighting proteins have been reported in the past years; however, a systematic study of the topic has been hindered because the secondary functions of proteins are usually found serendipitously by experiments. Toward systematic identification and study of moonlighting proteins, computational methods for identifying moonlighting proteins from several different information sources, database entries, literature, and large-scale omics data have been developed. In this study, an overview for finding moonlighting proteins is discussed. Then, the literature-mining method, DextMP, is applied to find new moonlighting

SUBMITTER: Jain A 

PROVIDER: S-EPMC6404977 | biostudies-literature | 2018 Nov

REPOSITORIES: biostudies-literature