Forecasting Demand for the Typhoid Conjugate Vaccine in Low- and Middle-income Countries.

ABSTRACT:

Background

The World Health Organization (WHO) released a position paper in March 2018 calling for integration of a novel typhoid conjugate vaccine (TCV) into routine immunization along with catch-up campaigns for children up to age 15. Gavi, the Vaccine Alliance, has committed funding to help resource-constrained countries introduce this vaccine. In this article, the Typhoid Vaccine Acceleration Consortium forecasts demand if WHO recommendations are followed.

Methods

We built a model of global TCV introductions between 2020 and 2040 to estimate the demand of the vaccine for 133 countries. We estimated each country's year of introduction by examining its estimated incidence of typhoid fever, its history of introducing new vaccines, and any knowledge we have of its engagement

SUBMITTER: Debellut F 

PROVIDER: S-EPMC6405267 | biostudies-literature | 2019 Mar

REPOSITORIES: biostudies-literature