An association between IL-10 promoter polymorphisms and diabetic nephropathy: a meta-analysis of case-control studies.

ABSTRACT:

Background

This study aimed to synthesize evidence on the association between IL-10 gene (-819 C/T, -1082 A/G, -592 A/C) polymorphisms and the risk of developing diabetic nephropathy.

Methods

A systematic literature search was done in health-related electronic databases. The search was limited to studies published in English until September 2017. We also checked the references of retrieved articles and relevant reviews for any additional studies. The methodological quality of the studies included in this review was assessed using the 'Scales for Quality Assessment'. The I ² test was used to quantify between-study heterogeneity. A value of I ² > 50% indicated substantial heterogeneity. For the pooled analysis, summary odds ratio (OR) and it

SUBMITTER: Naing C 

PROVIDER: S-EPMC6405406 | biostudies-literature | 2018 Dec

REPOSITORIES: biostudies-literature