Numerical investigations on bubble-induced jetting and shock wave focusing: application on a needle-free injection.

ABSTRACT: The formation of a liquid jet into air induced by the growth of a laser-generated bubble inside a needle-free device is numerically investigated by employing the compressible Navier-Stokes equations. The three co-existing phases (liquid, vapour and air) are assumed to be in thermal equilibrium. A transport equation for the gas mass fraction is solved in order to simulate the non-condensable gas. The homogeneous equilibrium model is used in order to account for the phase change process between liquid and vapour. Thermodynamic closure for all three phases is achieved by a barotropic Equation of State. Two-dimensional axisymmetric simulations are performed for a needle-free device for which experimental data are available and used for the validation of the developed model. The influence of th

SUBMITTER: Kyriazis N 

PROVIDER: S-EPMC6405452 | biostudies-literature | 2019 Feb

REPOSITORIES: biostudies-literature