Associations of Echocardiography Markers and Vascular Brain Lesions: The ARIC Study.

ABSTRACT: Background Associations between subtle changes in cardiac and cerebral structure and function are not well understood, with some studies suggesting that subclinical cardiac changes may be associated with markers of vascular brain insult. Methods and Results Data from the ARIC (Atherosclerosis Risk in Communities) Study (5th ARIC visit; 2011-2013; N=1974) were used to explore relationships between abnormalities of cardiac structure/function and subclinical brain disease and to test specific associations between those cardiac and vascular brain changes that share a common mechanism. In adjusted models white matter hyperintensities were 0.66 cm³ greater (95% confidence interval [CI] 0.08-1.25) for every 1-mm increase in left ventricular LV wall thickness and 0.64 cm³ gre

SUBMITTER: Johansen MC 

PROVIDER: S-EPMC6405621 | biostudies-literature | 2018 Dec

REPOSITORIES: biostudies-literature