Individual differences in EPA and DHA content of Atlantic salmon are associated with gene expression of key metabolic processes.

ABSTRACT: The aim of this study was to explore how individual differences in content of the omega-3 fatty acids EPA and DHA in skeletal muscle of slaughter-sized Atlantic salmon, are associated with expression of genes involved in key metabolic processes. All experimental fish were fed the same diet throughout life and fasted for 14 days prior to slaughter. Still, there were relatively large individual variations in EPA and DHA content of skeletal muscle. Higher DHA content was concurrent with increased expression of genes of the glycolytic pathway and the production of pyruvate and lactate, whereas EPA was associated with increased expression of pentose phosphate pathway and glycogen breakdown genes. Furthermore, EPA, but not DHA, was associated with expression of genes involved in insulin signalin

SUBMITTER: Horn SS 

PROVIDER: S-EPMC6405848 | biostudies-literature | 2019 Mar

REPOSITORIES: biostudies-literature