First-in-human clinical study of novel technique to diagnose malignant melanoma via thermal conductivity measurements.

ABSTRACT: Melanoma is an aggressive skin cancer that originates from melanocytes and, especially in the case of early-stage melanoma, is distributed adjacent to the epidermis and superficial dermis. Although early-stage melanoma can be distinguished from benign nevus via a dermoscopy, it is difficult to distinguish invasive melanoma in its early stages from in situ melanoma. Because invasive melanoma must undergo a sentinel lymph node biopsy to be diagnosed, a non-invasive method to detect the micro-invasion of early-stage melanoma is needed for dermato-oncologists. This paper proposes a novel quantitative melanoma identification method based on accurate measurements of thermal conductivity using a pen-shaped device. This method requires skin temperature data for one minute to determine the effectiv

SUBMITTER: Okabe T 

PROVIDER: S-EPMC6405870 | biostudies-literature | 2019 Mar

REPOSITORIES: biostudies-literature