Intravitreal bevacizumab versus ranibizumab: Effects on the vessels of the fellow non-treated eye.

ABSTRACT:

Purpose

To evaluate the effects of anti-vascular endothelial growth factors (anti-VEGF) on the vessels of the non-treated eyes following intravitreal injections.

Methods

In this prospective, non-randomized trial, a total of 38 patients were recruited. 21 patients received ranibizumab, and 17 patients received bevacizumab. Fundus photography was carried out at baseline immediately before injection and at 3 days, 7 days, and one month after the injections. Using image analysis software, measurements were summarized as the central retinal artery equivalent (CRAE) and central retinal vein equivalent.

Results

In non-treated eyes, CRAE decreased significantly from 153.23 ± 15.20 μm before injection to 148.77 ± 17.21 μm 3 days after intravitreal bevacizumab (P = 0.004

SUBMITTER: Peyman M 

PROVIDER: S-EPMC6407068 | biostudies-literature | 2019 Mar

REPOSITORIES: biostudies-literature