Effects of inhaler therapy on mortality in patients with tuberculous destroyed lung and airflow limitation.

ABSTRACT:

Purpose

Although patients with tuberculous destroyed lung (TDL) receive long-acting muscarinic antagonist (LAMA) inhaler therapy, its effectiveness is not clear. This study evaluated the effect of LAMA inhaler therapy on mortality in patients with TDL and airflow limitation.

Patients and methods

A retrospective cohort of 683 patients with TDL and airflow limitation was analyzed in this study. The mortality was compared between 177 patients treated with LAMA inhalers >360 days (LAMA group) and 506 patients not treated with LAMA inhalers or treated with LAMA inhalers for <360 days (non-LAMA group). Risk factors for mortality were analyzed with Cox proportional hazards models and survival analysis was performed after propensity score matching.

Results

Patients in the LAM

SUBMITTER: Kim HC 

PROVIDER: S-EPMC6407515 | biostudies-literature | 2019

REPOSITORIES: biostudies-literature