Wireless, battery-free optoelectronic systems as subdermal implants for local tissue oximetry.

ABSTRACT: Monitoring regional tissue oxygenation in animal models and potentially in human subjects can yield insights into the underlying mechanisms of local O₂-mediated physiological processes and provide diagnostic and therapeutic guidance for relevant disease states. Existing technologies for tissue oxygenation assessments involve some combination of disadvantages in requirements for physical tethers, anesthetics, and special apparatus, often with confounding effects on the natural behaviors of test subjects. This work introduces an entirely wireless and fully implantable platform incorporating (i) microscale optoelectronics for continuous sensing of local hemoglobin dynamics and (ii) advanced designs in continuous, wireless power delivery and data output for tether-free operation. Th

SUBMITTER: Zhang H 

PROVIDER: S-EPMC6408152 | biostudies-literature | 2019 Mar

REPOSITORIES: biostudies-literature