Enhancement in acoustic focusing of micro and nanoparticles by thinning a microfluidic device.

ABSTRACT: The manipulation of micro/nanoparticles has become increasingly important in biological and industrial fields. As a non-contact method for particle manipulation, acoustic focusing has been applied in sorting, enrichment and analysis of particles with microfluidic devices. Although the frequency and amplitude of acoustic waves and the dimensions of microchannels have been recognized as important parameters for acoustic focusing, the thickness of microfluidic devices has not been considered so far. Here, we report that thin glass microfluidic devices enhance acoustic focusing of micro/nanoparticles. It was found that the thickness of a microfluidic device strongly influences its ability to focus particles via acoustic radiation, because the energy propagation of acoustic waves is affected by

SUBMITTER: Ota N 

PROVIDER: S-EPMC6408367 | biostudies-literature | 2019 Feb

REPOSITORIES: biostudies-literature