Molecular characterization of aldehydes and ketones in particle phase of mainstream and sidestream cigarette smoke.

ABSTRACT: Aldehydes and ketones (AKs) in cigarette smoke are risk to humans and environment. Due to the complexity of itself and the interference of the smoke tar matrix, the aldehydes and ketones in particle phase (AKPs) of mainstream smoke (MSS) and sidestream smoke (SSS) have not been well investigated. In this study, the AKPs of MSS and SSS were derivatized into polar products by reaction with Girard T reagent. The derivatives were isolated rapidly by column chromatography and analysed by Fourier transform ion cyclotron resonance mass spectrometry (FT-ICR MS). Fifteen species of aldehydes and ketones were detected by positive ion electrospray ionization (ESI) FT-ICR MS: O_1-6, N₁O_1-4, N₂O_1-3 and N₃O_2-3. The total number

SUBMITTER: Chen X 

PROVIDER: S-EPMC6408401 | biostudies-literature | 2019 Feb

REPOSITORIES: biostudies-literature