Degradation kinetics of cold plasma-treated antibiotics and their antimicrobial activity.

ABSTRACT: Antibiotics, such as ofloxacin (OFX) and ciprofloxacin (CFX), are often detected in considerable concentrations in both wastewater effluents and surface water. This poses a risk to non-target organisms and to human health. The aim of this work was to study atmospheric cold plasma (ACP) degradation of antibiotics in water and meat effluent and to explore any residual antimicrobial activity of samples submitted to the plasma process. The results revealed that ACP successfully degraded the studied antibiotics and that the reaction mechanism is principally related to attack by hydroxyl radicals and ozone. According to the disk diffusion assay, the activity of both antibiotics was considerably reduced by the plasma treatment. However, a microdilution method demonstrated that CFX exhibited highe

SUBMITTER: Sarangapani C 

PROVIDER: S-EPMC6408491 | biostudies-literature | 2019 Mar

REPOSITORIES: biostudies-literature