Children with poorly controlled asthma: Randomized controlled trial of a home-based environmental control intervention.

ABSTRACT:

Background

Few trials have tested targeted environmental control (EC) interventions based on biomarkers of second hand smoke (SHS) exposure and allergen sensitization in reducing asthma emergency department (ED) visits in children with poorly controlled asthma.

Methods

Overall, 222 children with poorly controlled asthma were randomized into a home-based EC intervention (INT) or control (CON) group and followed for ED visits over 12 months. All children received allergen-specific IgE serologic testing and SHS exposure biomarker testing to inform the EC intervention. Pharmacy data was examined for asthma medication fills. Cox proportional hazards and multivariate regression models were performed to examine factors associated with repeat ED visits.

Results

There was no d

SUBMITTER: Butz AM 

PROVIDER: S-EPMC6408727 | biostudies-literature | 2019 Mar

REPOSITORIES: biostudies-literature