Adolescent Exploratory Strategies and Behavioral Types in the Multivariate Concentric Square Field^TM Test.

ABSTRACT: Adolescence is an important developmental phase with extensive changes in behavior due to remodeling of the brain and hormonal systems. Validation of animal behavioral tests in this age group is therefore of importance as differences to adult behavior are often not clarified. The aim of the present study was to investigate adolescent behavior in the multivariate concentric square field^TM (MCSF) test and its relationship to other common behavioral tests as well as to a literature dataset of adult animals. Sixty adolescent male Wistar rats were tested in the MCSF and one of four reference tests; the elevated plus maze, the open field with or without start box, or the social play behavior test. Additionally, 12 animals were tested twice in the MCSF. When analyzing the first encount

SUBMITTER: Lundberg S 

PROVIDER: S-EPMC6409336 | biostudies-literature | 2019

REPOSITORIES: biostudies-literature