Genetic architecture and candidate genes detected for chicken internal organ weight with a 600 K single nucleotide polymorphism array.

ABSTRACT:

Objective

Internal organs indirectly affect economic performance and well-being of animals. Study of internal organs during later layer period will allow full utilization of layer hens. Hence, we conducted a genome-wide association study (GWAS) to identify potential quantitative trait loci or genes that potentially contribute to internal organ weight.

Methods

A total of 1,512 chickens originating from White Leghorn and Dongxiang Blue-Shelled chickens were genotyped using high-density Affymetrix 600 K single nucleotide polymorphism (SNP) array. We conducted a GWAS, linkage disequilibrium analysis, and heritability estimated based on SNP information by using GEMMA, Haploview and GCTA software.

Results

Our results displayed that internal organ weights show moderate to hi

SUBMITTER: Dou T 

PROVIDER: S-EPMC6409475 | biostudies-literature | 2019 Mar

REPOSITORIES: biostudies-literature