IPCT: Integrated Pharmacogenomic Platform of Human Cancer Cell Lines and Tissues.

ABSTRACT: : (1) Motivation: The exponential increase in multilayered data, including omics, pathways, chemicals, and experimental models, requires innovative strategies to identify new linkages between drug response information and omics features. Despite the availability of databases such as the Cancer Cell Line Encyclopedia (CCLE), the Cancer Therapeutics Response Portal (CTRP), and The Cancer Genome Atlas (TCGA), it is still challenging for biologists to explore the relationship between drug response and underlying genomic features due to the heterogeneity of the data. In light of this, the Integrated Pharmacogenomic Database of Cancer Cell Lines and Tissues (IPCT) has been developed as a user-friendly way to identify new linkages between drug responses and genomic features, as thes

SUBMITTER: Shoaib M 

PROVIDER: S-EPMC6409836 | biostudies-literature | 2019 Feb

REPOSITORIES: biostudies-literature