Immunological characterization of onion (Allium cepa) allergy.

ABSTRACT:

Introduction

Onion (Allium cepa) handling can induce contact dermatitis, rhinoconjunctivitis and asthma. However, only sporadic reports exist on allergic reactions to onion consumption.

Aim

We describe herein a case of a 35-year-old man who had an episode of anaphylaxis following cooked onion ingestion. We evaluated onion-specific IgE, the possible cross-reactivity between onion and peach and lymphocyte proliferation in response to onion.

Material and methods

Specific IgE was evaluated using two techniques: skin test and ImmunoCAP technology. Cross-reactivity between onion and peach was evaluated by IgE-ELISA inhibition test. As for lymphocyte proliferation, blood mononuclear cells were stained with CFSE dye and cultured with an in-house onion extract. Proliferation a

SUBMITTER: Albanesi M 

PROVIDER: S-EPMC6409889 | biostudies-literature | 2019 Feb

REPOSITORIES: biostudies-literature