Facile Fabrication of Fluorescent Inorganic Nanoparticles with Diverse Shapes for Cell Imaging.

ABSTRACT: In the present work, we describe a facile and general method of fabricating fluorescent inorganic nanoparticles with diverse shapes for cell imaging application. The hematite (α-Fe₂O₃) nanoparticles (HNPs) with three different shapes (i.e., spindle shape, ellipsoidal shape and quasi-spherical shape) were first prepared as model systems in consideration of good biocompatibility and the controllable morphology of α-Fe₂O₃. Three fluorescent HNPs with different shapes were readily achieved via one-pot sol-gel reaction of AIE luminogen-functionalized siloxane (AIEgen-Si(OCH₃)₃) and TEOS in the presence of PVP-stabilized HNPs. Due to the fluorescence originating from the thin AIEgens-contained SiO₂ shell around the HNPs, their photoluminescent intensities can be tuned by changing the concentrati

SUBMITTER: Wang G 

PROVIDER: S-EPMC6410410 | biostudies-literature | 2019 Jan

REPOSITORIES: biostudies-literature