Challenges of P300 Modulation Using Transcranial Alternating Current Stimulation (tACS).

ABSTRACT: The P300 component of the event-related potential (ERP) is a well investigated phenomenon in the human electroencephalogram (EEG) and has been related to stimulus processing and attentional mechanisms. Event-related oscillations (ERO) represent a potential mechanism responsible for generating the ERP. In particular, oscillatory activity in the delta and theta frequency range has been associated with the generation of the P300 component. Transcranial Alternating Current Stimulation (tACS) is capable of modulating oscillatory brain activity in a frequency-specific manner. In this study, we aimed to modulate P300 amplitude using tACS by stimulating the individual ERO involved in the generation of the P300 component. TACS was applied precisely in time to the target P300 occurring in a visual o

SUBMITTER: Popp F 

PROVIDER: S-EPMC6411790 | biostudies-literature | 2019

REPOSITORIES: biostudies-literature