Graph theory analysis of DTI tractography in children with traumatic injury.

ABSTRACT:

Objective

To evaluate brai structural connectivity in children with traumatic injury (TI) following a motor vehicle accident using graph theory analysis of DTI tractography data.

Methods

DTI scans were acquired on a 3 T Philips scanner from children aged 8-15 years approximately 2 months post-injury. The TI group consisted of children with traumatic brain injury (TBI; n = 44) or extracranial injury (EI; n = 23). Healthy control children (n = 36) were included as an age-matched comparison group. A graph theory approach was applied to DTI tractography data to investigate injury-related differences in connectivity network characteristics. Group differences in structural connectivity evidenced by graph metrics including efficiency, strength, and modularity were assessed using th

SUBMITTER: Watson CG 

PROVIDER: S-EPMC6412099 | biostudies-literature | 2019

REPOSITORIES: biostudies-literature