Multi-Stage Particle Separation based on Microstructure Filtration and Dielectrophoresis.

ABSTRACT: Particle separation is important in chemical and biomedical analysis. Among all particle separation approaches, microstructure filtration which based particles size difference has turned into one of the most commonly methods. By controlling the movement of particles, dielectrophoresis has also been widely adopted in particle separation. This work presents a microfluidic device which combines the advantages of microfilters and dielectrophoresis to separate micro-particles and cells. A three-dimensional (3D) model was developed to calculate the distributions of the electric field gradient at the two filter stages. Polystyrene particles with three different sizes were separated by micropillar array structure by applying a 35-Vpp AC voltage at 10 KHz. The blocked particles were pushed off the

SUBMITTER: Yin D 

PROVIDER: S-EPMC6412275 | biostudies-literature | 2019 Jan

REPOSITORIES: biostudies-literature