Optimized preoperative motor cortex mapping in brain tumors using advanced processing of transcranial magnetic stimulation data.

ABSTRACT:

Background and objective

Transcranial magnetic stimulation (TMS) is a useful technique to help localize motor function prior to neurosurgical procedures. Adequate modelling of the effect of TMS on the brain is a prerequisite to obtain reliable data.

Methods

Twelve patients were included with perirolandic tumors to undergo TMS-based motor mapping. Several models were developed to analyze the mapping data, from a projection to the nearest brain surface to motor evoked potential (MEP) amplitude informed weighted average of the induced electric fields over a multilayer detailed individual head model. The probability maps were compared with direct cortical stimulation (DCS) data in all patients for the hand and in three for the foot. The gold standard was defined as the results o

SUBMITTER: Seynaeve L 

PROVIDER: S-EPMC6413351 | biostudies-literature | 2019

REPOSITORIES: biostudies-literature