A Comparative Study of Fractionated Versus Single Dose Injection for Spinal Anesthesia During Cesarean Section in Patients with Pregnancy-Induced Hypertension.

ABSTRACT:

Background

Local anesthetics for spinal anesthesia in one-single injection are known to induce more severe hypotension than a fractionated dose in healthy obstetric patients. Hypotension in obstetric patients with pregnancy-induced hypertension, including preeclampsia, during spinal anesthesia, could compromise fetal well-being.

Objectives

This study aimed to compare the mean arterial pressure (MAP), the total dose of ephedrine required, and level of sensory blockade between the fractionated-dose and single-dose spinal anesthesia injection in obstetric patients with pregnancy-induced hypertension who underwent a cesarean section.

Methods

This single-blind randomized clinical trial was conducted from January to April 2018 after being approved by the Research Ethics Com

SUBMITTER: Nugroho AM 

PROVIDER: S-EPMC6413406 | biostudies-literature | 2019 Feb

REPOSITORIES: biostudies-literature