Associations between fine particulate matter and changes in lipids/lipoproteins among midlife women.

ABSTRACT: Fine particles (PM_2.5) are known to increase risks of cardiovascular diseases, but it is unclear how they affect plasma lipid levels. In this study, we examined the associations between PM_2.5 exposure and lipid/lipoprotein levels from 2289 midlife women enrolled in the longitudinal Study of Women's Health Across the Nation. The average exposure to PM_2.5 and gaseous co-pollutants during the prior one year, six months, 30 days, and one day were estimated for each woman based on U.S. Environmental Protection Agency ambient monitoring data. Blood samples were collected annually from 1999 to 2005 and analyzed for lipids/lipoproteins. Mixed-effect models were used to account for repeated measures for each woman, adjusted for demographic, health and behavior covar

SUBMITTER: Wu XM 

PROVIDER: S-EPMC6413864 | biostudies-literature | 2019 Mar

REPOSITORIES: biostudies-literature