Enantioselective Construction of Tertiary Boronic Esters by Conjunctive Cross-Coupling.

ABSTRACT: Catalytic enantioselective conjunctive cross-coupling has been developed to construct tertiary alkylboronic esters. These reactions occur with good yield and enantioselectivity for a range of substrates. Mechanistic experiments reveal aspects of the catalytic cycle that allow hindered substrates to react without significant complicating side reactions.

SUBMITTER: Myhill JA 

PROVIDER: S-EPMC6414220 | biostudies-literature | 2018 Sep

REPOSITORIES: biostudies-literature