Thresholds of ultrasound synovial abnormalities for knee osteoarthritis - a cross sectional study in the general population.

ABSTRACT:

Objective

To establish "normal" ranges for synovial thickness and effusion detected by ultrasound (US) and to determine cut-offs associated with knee pain (KP) and radiographic knee osteoarthritis (RKOA) in the community.

Methods

147 women and 152 men ≥40 years old were randomly selected from the Nottingham KP and Related Health in the Community (KPIC) cohort (n = 9506). The "normal" range was established using the percentile method in 163 participants who had no KP and no RKOA. Optimal (maximum sensitivity and specificity) and high specificity (90%) cut-offs were established using receiver operating characteristic (ROC) curve analysis in a comparison between people with both KP and RKOA and normal controls.

Results

Effusion and synovial hypertrophy differed by gender

SUBMITTER: Sarmanova A 

PROVIDER: S-EPMC6414397 | biostudies-literature | 2019 Mar

REPOSITORIES: biostudies-literature