Gold-decorated magnetic nanoparticles design for hyperthermia applications and as a potential platform for their surface-functionalization.

ABSTRACT: The integration of noble metal and magnetic nanoparticles with controlled structures that can couple various specific effects to the different nanocomposite in multifunctional nanosystems have been found interesting in the field of medicine. In this work, we show synthesis route to prepare small Au nanoparticles of sizes  = 3.9 ± 0.2 nm attached to Fe₃O₄ nanoparticle cores ( = 49.2 ± 3.5 nm) in aqueous medium for potential application as a nano-heater. Remarkably, the resulted Au decorated PEI-Fe₃O₄ (Au@PEI-Fe₃O₄) nanoparticles are able to retain bulk magnetic moment M_S = 82-84 Am²/kg_Fe3O4, with the Verwey transition observed at T_V = 98 K. In addition, the in vitro cytotoxici

SUBMITTER: Leon Felix L 

PROVIDER: S-EPMC6414712 | biostudies-literature | 2019 Mar

REPOSITORIES: biostudies-literature