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Comparative gene expression analysis of planktonic Porphyromonas gingivalis ATCC 33277 in the presence of a growing biofilm versus planktonic cells.

ABSTRACT: BACKGROUND:Porphyromonas gingivalis, a microorganism residing in the oral cavity within complex multispecies biofilms, is one of the keystone pathogens in the onset and progression of periodontitis. In this in vitro study, using DNA microarray, we investigate the differential gene expression of Porphyromonas gingivalis ATCC 33277 when growing in the presence or in absence of its own monospecies biofilm. RESULTS:Approximately 1.5% of genes (28 out of 1909 genes, at 1.5 fold change or more, p-value

SUBMITTER: Sanchez MC 

PROVIDER: S-EPMC6417203 | biostudies-literature | 2019 Mar

REPOSITORIES: biostudies-literature

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Comparative gene expression analysis of planktonic Porphyromonas gingivalis ATCC 33277 in the presence of a growing biofilm versus planktonic cells.

Sánchez María C MC   Sánchez María C MC   Romero-Lastra Patricia P   Ribeiro-Vidal Honorato H   Llama-Palacios Arancha A   Figuero Elena E   Herrera David D   Sanz Mariano M  

BMC microbiology 20190312 1

<h4>Background</h4>Porphyromonas gingivalis, a microorganism residing in the oral cavity within complex multispecies biofilms, is one of the keystone pathogens in the onset and progression of periodontitis. In this in vitro study, using DNA microarray, we investigate the differential gene expression of Porphyromonas gingivalis ATCC 33277 when growing in the presence or in absence of its own monospecies biofilm.<h4>Results</h4>Approximately 1.5% of genes (28 out of 1909 genes, at 1.5 fold change  ...[more]

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