Changes of intestinal flora in patients with systemic lupus erythematosus in northeast China.

ABSTRACT:

Objective

The human gut harbors diverse microbes that play a fundamental role in the well-being of their hosts. Microbes can cause autoimmunity, trigger autoimmunity in genetically susceptible individuals or prevent autoimmunity. There were reports about intestinal flora changes in Systemic Lupus Erythematosus (SLE) patients, but no data were available in northeast China. In this study, we investigated the intestinal flora changes of SLE patients in Heilongjiang province located in northeast China.

Methods

Feces from 16 SLE patients and 14 healthy volunteers were employed to extract bacterial DNA, amplify 16s RNA of bacteria, and analyze the biological information by sequencing. The statistical analysis used the SPSS version of 17.

Result

We found that there were 1 ph

SUBMITTER: Wei F 

PROVIDER: S-EPMC6417672 | biostudies-literature | 2019

REPOSITORIES: biostudies-literature