Use of a novel computerized decision aid for aneuploidy screening: a randomized controlled trial.

ABSTRACT:

Purpose

To assess whether knowledge following use of a decision aid (DA) for aneuploidy screening and testing is inferior to knowledge in women who saw a genetic counselor (GC) only.

Methods

This is a randomized controlled noninferiority trial of pregnant women at ≤22 weeks. Women who were scheduled for GC were randomly allocated to use a DA before GC or to GC alone. The primary outcome was knowledge score, comparing women who had used the DA only to those who saw GC alone. Analysis was by intent to treat.

Results

Between January and October 2017, 197 women were randomized, 105 to GC only and 92 to DA use before GC. Demographics and baseline knowledge were similar between groups. Mean knowledge score following DA use was not inferior to mean knowledge score following

SUBMITTER: Carlson LM 

PROVIDER: S-EPMC6417985 | biostudies-literature | 2019 Apr

REPOSITORIES: biostudies-literature