Estimates of case-fatality ratios of measles in low-income and middle-income countries: a systematic review and modelling analysis.

ABSTRACT:

Background

In the 21st century, increases in immunisation coverage and decreases in under-5 mortality have substantially reduced the global burden of measles mortality. However, the assessment of measles mortality burden is highly dependent on estimates of case-fatality ratios for measles, which can vary according to geography, health systems infrastructure, prevalence of underlying risk factors, and measles endemicity. With imprecise case-fatality ratios, there is continued uncertainty about the burden of measles mortality and the effect of measles vaccination. In this study, we aimed to update the estimations of case-fatality ratios for measles, to develop a prediction model to estimate case-fatality ratios across heterogeneous groupings, and to project future case-fatality ratio

SUBMITTER: Portnoy A 

PROVIDER: S-EPMC6418190 | biostudies-literature | 2019 Apr

REPOSITORIES: biostudies-literature