The protective role of rs56103835 against breast cancer onset in the Iranian population.

ABSTRACT:

Background

Breast cancer is one of the most common types of cancer among women and the highest cause of death due to cancer among women aged 40-45. SNPs can be used to identify disease-related genes such as cancer as they can be genetic markers. Furthermore, SNPs in the molecular-level miRNA structure are also associated with a set of cancers. Studies have shown that miR-323b plays a tumor suppressor role by reducing the tissues and serum of the affected individuals. So far, no study regarding rs56103835 polymorphism in the precursor of miR-323b has been conducted in the breast cancer. In this study, the association of this SNP with the incidence of breast cancer in the Iranian population has been investigated.

Method

In order to correlate rs56103835 polymorphism with breast

SUBMITTER: Naderi N 

PROVIDER: S-EPMC6418365 | biostudies-literature | 2019 Mar

REPOSITORIES: biostudies-literature