Intravascular NIRF Molecular Imaging Approaches in Coronary Artery Disease.

ABSTRACT: Progression of vulnerable coronary atherosclerotic plaques underlies the majority of acute myocardial infarction and sudden cardiac death episodes. Recent advances in biological/molecular imaging technology are now enabling the accurate identification of high-risk plaques and stents in living subjects. Due to their smaller caliber and susceptibility to cardiorespiratory motion, noninvasive molecular imaging of human coronary arteries remains challenging. Therefore, intravascular high-resolution molecular imaging approaches appear necessary to resolve molecular features of human coronary arteries and stents. Here we present recent progress in intravascular near-infrared fluorescence (NIRF) molecular imaging, including the evolution from standalone NIRF systems to those integrated with struc

SUBMITTER: Hara T 

PROVIDER: S-EPMC6419760 | biostudies-literature | 2016 Apr

REPOSITORIES: biostudies-literature