DASHR 2.0: integrated database of human small non-coding RNA genes and mature products.

ABSTRACT:

Motivation

Small non-coding RNAs (sncRNAs, <100 nts) are highly abundant RNAs that regulate diverse and often tissue-specific cellular processes by associating with transcription factor complexes or binding to mRNAs. While thousands of sncRNA genes exist in the human genome, no single resource provides searchable, unified annotation, expression and processing information for full sncRNA transcripts and mature RNA products derived from these larger RNAs.

Results

Our goal is to establish a complete catalog of annotation, expression, processing, conservation, tissue-specificity and other biological features for all human sncRNA genes and mature products derived from all major RNA classes. DASHR (Database of small human non-coding RNAs) v2.0 database is the first that integrates

SUBMITTER: Kuksa PP 

PROVIDER: S-EPMC6419920 | biostudies-literature | 2019 Mar

REPOSITORIES: biostudies-literature