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High Environmental Stability of Hepatitis B Virus and Inactivation Requirements for Chemical Biocides.


ABSTRACT: Hepatitis B virus (HBV) infection is considered a major public health problem worldwide, and a significant number of reports on nosocomial and occupational outbreaks have been reported. This systematic investigation of HBV stability and susceptibility to different antiseptics revealed that HBV infectivity was very stable, with a half-life of >22 days at 37°C. At 4°C, infectivity was barely reduced for up to 9 months. Different alcohols and commercially available hand antiseptics had a virucidal effect against HBV. We propose that very strict compliance with established hygienic guidelines should be mandatory to avoid and prevent HBV infections.

SUBMITTER: Than TT 

PROVIDER: S-EPMC6420165 | biostudies-literature | 2019 Mar

REPOSITORIES: biostudies-literature

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High Environmental Stability of Hepatitis B Virus and Inactivation Requirements for Chemical Biocides.

Than Thoa Thi TT   Jo Eunji E   Todt Daniel D   Nguyen Phuong Hong PH   Steinmann Jochen J   Steinmann Eike E   Windisch Marc P MP  

The Journal of infectious diseases 20190301 7


Hepatitis B virus (HBV) infection is considered a major public health problem worldwide, and a significant number of reports on nosocomial and occupational outbreaks have been reported. This systematic investigation of HBV stability and susceptibility to different antiseptics revealed that HBV infectivity was very stable, with a half-life of >22 days at 37°C. At 4°C, infectivity was barely reduced for up to 9 months. Different alcohols and commercially available hand antiseptics had a virucidal  ...[more]

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